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Nebraska vs. Illinois Prediction, Odds, Picks For College Football Week

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FOX Sports Research

The Illinois Fighting Illini kick off against the Nebraska Cornhuskers on Friday in a Week 10 college football matchup on FOX.

  • Illinois: +164
  • Nebraska: -198
  • Spread

    • Illinois +4.5: -108
    • Nebraska -4.5: -112

    Over/Under

    • Over 49.5: -115
    • Under 49.5: -105

     Nebraska Cornhuskers Illinois Fighting Illini Nebraska @ Illinois Prediction, Pick

    From FOX Sports Research: 

    • Nebraska has lost its last three games after starting 5-0. During this three-game losing streak, the Cornhuskers are averaging 13.7 points per game.
    • Collin Dixon leads Illinois with 781 receiving yards, third in the Big Ten.
    • Nebraska is giving up 15.6 points per game, fifth-fewest in the Big Ten.

    Nebraska CornhuskersThe Pick: Nebraska Moneyline

    How to Watch Illinois vs. Nebraska 

    • Date: Friday, Nov. 6, 2026
    • Time: 8:00 p.m. ET
    • TV: FOX
    • Stream: Watch 3 days free on FOX One, FOXSports.com, FOX Sports App
    • Location: GiesMemorial Stadium, Champaign, IL

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